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Legal category
POM-VPS (previously PML)
Pharmaceutical precautions
Do not store above 25C. Protect from light
Presentation
Protect from light.
Store blisters below 25°C.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with national requirements. EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with the product or used container.
 
Dosage and administration
 

Amounts to be administered and administration route

Vectin is to be administered orally as a single treatment. The product contains a flavour and will be taken voluntarily by most horses. The product can either be administered by hand, similar to a treat, or mixed with a small amount of feed. It should be ensured that the horse consumes the entire dose.
 
The dose scheme provides for a minimum dose of 0.2 mg ivermectin per kg body weight.

One chewable tablet is adequate for the treatment of up to 110 kg body weight. For higher body weights, a corresponding number of chewable tablets should be chosen according to the following dose scheme:
 

 Body weight of the horse (kg):

Number of Vectin chewable tablets to be administered:

60 to 110

1

111 to 220

2

221 to 330

3

331 to 440

4

441 to 550

5

551 to 660

6

etc.

etc.

Mild transitory signs (slowed pupillary light response and depression) have been seen at a dose of 1.8 mg/kg. Other signs seen at higher doses include mydriasis, ataxia, tremors, stupor, coma and death. The less severe sign have been transitory. There is no known antidote but if signs of toxicity appear symptomatic therapy is recommended.

 

Withdrawal period

Meat and offal: 52 days

The product is not authorised for use in mares producing milk for human consumption.

Special warnings for each target species

Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
Underdosing, which may be due to underestimation of body weight or misadministration of the product.

Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. faecal egg count reduction test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

Resistance to ivermectin has been reported in Parascaris equorum in horses. Therefore, the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.

Veterinary advice should be given on appropriate dosing programs and stock management to achieve adequate parasite control and reduce the likelihood of anthelmintic resistance developing. In the event that a product is suspected of being ineffective, the animal owner is advised to seek veterinary advice

 

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VECTIN TABLETS
Contra-indications, warnings, etc

Antiparasitic for the treatment of horses infected with adult and immature stages of the following gastro-intestinal nematodes, lungworms, microfilariae and stomach bots:

Large strongyles
Strongylus vulgaris           Ad
ults and 4th stage larvae (arterial stages)

Strongylus edentatus    adults and 4th stage larvae (tissue stages)

Strongylus equinus                                                      adults

Small strongyles
Triodontophorus
spp.                            adults

Triodontophorus brevicauda

Triodontophorus serratus

Triodontophorus tenuicollis

Craterostomum acuticaudatum                  adults

Coronocyclus spp.                                                       adults and intraluminal 4th stage larvae

Coronocyclus coronatus

Coronocyclus labiatus

Coronocyclus labratus

Cyathostomum spp.                 lts and intraluminal 4th stage larvae

Cyathostomum catinatum

Cyathostomum pateratum

 

Cylicocyclus spp.                                                         adults and intraluminal 4th stage larvae

Cylicocyclus ashworthi

Cylicocyclus elongatus

Cylicocyclus insigne

Cylicocyclus leptostomum

Cylicocyclus nassatus

Cylicocyclus radiatus

 

Cylicodontophorus spp.                            adults and intraluminal 4th stage larvae

Cylicodontophorus bicoronatus

Cylicostephanus spp.                                       adults and intraluminal 4th stage larvae

Cylicostephanus asymetricusCylicostephanus bidentatus

Cylicostephanus calicatus

Cylicostephanus goldi

Cylicostephanus longibursatus

Cylicostephanus minutus

Gyalocephalus capitatus                                             adults and intraluminal 4th stage larvae

Parapoteriostomum spp.                                              adults and intraluminal 4th stage larvae

          Parapoteriostomum euproctus

          Parapoteriostomum mettami

Petrovinema spp.                                                         adults and intraluminal 4th stage larvae

          Petrovinema poculatum

Poteriostomum spp.                                         adults and intraluminal 4th stage larvae

          Poteriostomum imparidentatum

          Poteriostomum ratzii

Habronema muscae     adults and skin larvae


Pinworms

Oxyuris equi                                                    adults and immature stages

Large-mouth stomach worms
Draschia
spp.                                                  skin larvae

Ascarids
Parascaris equorum
                                        adults, 3rd and 4th stage larvae

 Hairworms
Trichostrongylus axei 
                                    adults

Neck threadworms                             

Onchocerca spp.                                                         microfilariae

 Stomach bots
Gasterophilus
spp.                                                       all larval stages

Lungworms
Dictyocaulus arnfieldi
                                    adults and immature stages

Intestinal threadworms
Strongyloides westeri
                                       adults

Dermatitis caused by skin larvae of Habronema and Draschia spp. (summer sores) or by Onchocerca sp. microfilariae (skin onchocercosis).

Contraindications

Do not use in horses weighing less than 60 kg.
Do not use in horses known to be hypersensitive to the active ingredient or any of the excipients.
Vectin is registered for horses and should not be used in other animal species. After the administration of ivermectin to dogs, cases of intolerance with a fatal outcome have been reported, especially in Collies, Old English Sheepdogs and related breeds or crosses, and also in turtles/tortoises.
Dogs or cats may be adversely affected by the ivermectin in this product if they are allowed to ingest dropped or discarded tablets or have access to used packaging material.
Occasionally, some horses heavily infected with Onchocerca microfilariae have developed oedema and pruritus following dosing, assumed to be due to the death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable.
On very rare occasions, colic, diarrhoea and anorexia have been reported post treatment, in particular when there is heavy worm burden. On very rare occasions, allergic reactions such as hypersalivation, lingual oedema and urticaria, tachycardia, congested mucous membranes, and subcutaneous oedema have been reported following treatment with the product.
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
•Over-frequent and repeated use of anthelmintics from the same class, over an extended period of time.
•Underdosing, which may be due to underestimation of body weight or maladministration of the product.
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. faecal egg count reduction test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Resistance to ivermectin has been reported in Parascaris equorum in horses. Therefore, the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Veterinary advice should be given on appropriate dosing programmes and stock management to achieve adequate parasite control and reduce the likelihood of anthelmintic resistance developing. In the event that a product is suspected of being ineffective, the animal owner is advised to seek veterinary advice.
Studies have demonstrated there are no adverse effects when horses are administered up to three times the recommended dose.
Mild transitory signs (slowed pupillary light response and depression) have been seen at a dose of 1.8 mg/kg. Other signs seen at higher doses include mydriasis, ataxia, tremors, stupor, coma and death. The less severe signs have been transitory. There is no known antidote but if signs of toxicity appear, symptomatic therapy is recommended.
Operator warnings
Do not eat, drink or smoke while handling the product.
Wash your hands thoroughly with water and soap immediately after use of the product.
Since this veterinary medicinal product can irritate eyes, any contact with the eyes should be avoided while using the product. If accidental exposure occurs, flush eyes immediately with plenty of water.
In case of accidental ingestion or eye irritation, seek medical advice immediately and show the package leaflet or the label to the physician.
Withdrawal period
Meat and offal: 52 days.
The product is not authorised for use in mares producing milk for human consumption.
For animal treatment only. Keep out of the reach and sight of children.


 

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